Gobbi A, Albanese D, Iorio F, Jurman G and . JS (2016). BiRewire: High-performing routines for the randomization of a bipartite graph (or a binary event matrix), undirected and directed signed graph preserving degree distribution (or marginal totals). R package version 3.0.1, http://www.ebi.ac.uk/~iorio/BiRewire.